Locations:
Luis R. Hoyos, M.D.
Board-certified
Obstetrics and Gynecology
Reproductive Endocrinology and Infertility
Luis R. Hoyos, M.D., is double board-certified in Obstetrics and Gynecology and Reproductive Endocrinology and Infertility. He provides fertility care at IVF FLORIDA’s Coral Gables, Margate, and Pembroke Pines locations. Known for his warm, personalized approach, Dr. Hoyos brings a deep commitment to patient care and a passion for the science behind reproductive medicine.
Originally from Colombia, Dr. Hoyos earned his medical degree before moving to the U.S. to complete his OB/GYN residency at Detroit Medical Center/Wayne State University, where he served as Academic Chief Resident and earned numerous awards for academic and surgical excellence. He completed his fellowship in Reproductive Endocrinology and Infertility at the David Geffen School of Medicine at UCLA. As one of a select group of physicians named a Clinical Reproductive Scientist (CREST) Scholar by the NICHD and ASRM, Dr. Hoyos is dedicated to advancing fertility care through both research and clinical practice, while serving as the research director for IVF FLORIDA, where he collaborates on nationwide research and oversees clinical trials.
As a result of his research endeavors, Dr. Hoyos has produced more than 35 peer-reviewed publications and book chapters on fertility outcomes, reproductive genetics, and fertility preservation, among several other topics in reproductive medicine. He continues to publish and present at national and international medical conferences.
Fluent in English and Spanish, Dr. Hoyos believes in staying present with his patients—listening closely, offering reassurance, and providing clarity. He considers patient resilience his greatest inspiration and strives to bring not only clinical excellence but also human connection to his work each day.
Locations:
Education
Residency: Detroit Medical Center/Wayne State University, Detroit, MI
Fellowship: David Geffen School of Medicine at UCLA, Los Angeles, CA
Awards
Fellow Abstract Winner at the Midwest Reproductive Symposium International 2019
AAGL Recognition of Excellence in Minimally Invasive Gynecology 2017
Detroit Medical Center/Wayne State University Department of Obstetrics & Gynecology Excellence in Academic Achievement 2014, 2015, 2016 and 2017
Kamran S. Moghissi, M.D. Award 2015-16
Highest Colombian National Medical Exam Score 2011
Professional Organizations
Fellow
The American College of Obstetricians & Gynecologists
Member
The American Society for Reproductive Medicine
Associate member
The Society for Reproductive Endocrinology and Infertility
Member
Florida Society of Reproductive Endocrinology and Infertility
Select Publications
Comparing blastulation of surgically retrieved sperm with ejaculated sperm in donor oocyte cycles. Namath A, Flannagan K, Le K, Ghofranian A, Reckhow J, Eubanks A, Rambhatla A, Homer M, Uhler ML, Hoyos LR, Marinaro J, Romanski P, Roth L. Fertil Steril. 2025 Jun 2:S0015-0282(25)00263-8. doi: 10.1016/j.fertnstert.2025.05.002. PMID: 40348156
Zalles LX, Le K, Jahandideh S, Wang J, Homer MV, Uhler ML, Hoyos LR, Devine K, Bruno-Gaston J. Impact of time interval from cesarean delivery to frozen embryo transfer on reproductive and neonatal outcomes. Fertil Steril. 2024 Sep;122(3):455-464. doi: 10.1016/j.fertnstert.2024.04.023. Epub 2024 Apr 23. PMID: 38663505
Clain E, Kaizer LK, Sammel MD, Wang J, Homer M, Uhler M, Hoyos LR, Devine K, Polotsky AJ. Mild obesity does not affect perinatal outcome in gestational carrier cycles. Hum Reprod. 2024 Jun 3;39(6):1316-1322. doi: 10.1093/humrep/deae079. PMID: 38636947
Zalles LX, Le K, Jahandideh S, Wang J, Homer MV, Uhler ML, Hoyos LR, Devine K, Bruno-Gaston J. Impact of time interval from cesarean delivery to frozen embryo transfer on reproductive and neonatal outcomes. Fertil Steril. 2024 Sep;122(3):455-464. doi: 10.1016/j.fertnstert.2024.04.023. Epub 2024 Apr 23. PMID: 38663505
Clain E, Kaizer LK, Sammel MD, Wang J, Homer M, Uhler M, Hoyos LR, Devine K, Polotsky AJ. Mild obesity does not affect perinatal outcome in gestational carrier cycles. Hum Reprod. 2024 Jun 3;39(6):1316-1322. doi: 10.1093/humrep/deae079. PMID: 38636947
Lersten IL, Grau L, Jahandideh S, Devine K, Zalles L, Plosker SM, Imudia AN, Hoyos LR, Uhler ML, Homer M, Roeca C, Sammel MD, Polotsky AJ. High estradiol levels in fresh embryo transfer cycles are not associated with detrimental impact on birth. J Assist Reprod Genet. 2024 Apr;41(4):893-902. doi: 10.1007/s10815-024-03062-4. Epub 2024 Apr 11. PMID: 38600428
Dilday E, Gigg M, Hoyos L, Quinn M, Markovic D, Kroener L. Luteal phase support with progesterone does not improve pregnancy rates in patients undergoing ovarian stimulation with letrozole. Reprod Biomed Online. 2022 Sep 20:S1472-6483(22)00705-2. doi: 10.1016/j.rbmo.2022.09.012. PMID: 36396533
Hoyos LR, Visser JA, McLuskey A, Chazenbalk GD, Grogan TR, Dumesic DA. Loss of anti-Müllerian hormone (AMH) immunoactivity due to a homozygous AMH gene variant rs10417628 in a woman with classical polycystic ovary syndrome (PCOS). Hum Reprod. 2020 Oct 1;35(10):2294-2302. doi: 10.1093/humrep/deaa199. PMID: 32918081
Hoyos-Martinez A, Hoyos LR, Putra M, Armstrong AA, Rambhatla A, Allen-Rhodes W, Brennan K. Availability of Fertility Preservation Information on the Websites of U.S. News and World Report Top-Ranked Pediatric Cancer Programs. J Adolesc Young Adult Oncol. 2020 May 27. doi: 10.1089/jayao.2020.0003. PMID: 32460587
Hoyos LR, Putra M, Armstrong AA, Cheng CY, Riestenberg CK, Schooler TA, Dumesic DA. Measures of Patient Dissatisfaction with Health Care in Polycystic Ovary Syndrome: Retrospective Analysis. J Med Internet Res. 2020 Apr 21;22(4):e16541. doi: 10.2196/16541. PMID: 32314967
Hoyos LR, Cheng CY, Brennan K, Hubert G, Wang B, Buyalos RP, Quinn M, Shamonki M. Euploid rates among oocyte donors: is there an optimal age for donation? J Assist Reprod Genet. 2020 Jan 18. doi: 10.1007/s10815-020-01694-w. PMID: 31955339
Hoyos LR, Tamakuwala S, Rambhatla A, Brar H, Vilchez G, Allsworth J, Rodriguez-Kovacs J, Awonuga A. Risk Factors for Cervical Ectopic Pregnancy. J Gynecol Obstet Hum Reprod. 2019 Dec 4:101665. doi: 10.1016/j.jogoh.2019.101665. PMID: 31811970
Hoyos-Martinez A, Hoyos LR, Comkornruecha M, Diaz A. Primary Ovarian Insufficiency in an Adolescent Population: Clinical Phenotype and Diagnostic Approach. J Pediatr Endocrinol Metab. 2019 Sep 25;32(9):979-985. doi: 10.1515/jpem-2019-0083. PMID: 31301677
Dumesic DA, Phan JD, Leung KL, Grogan TR, Ding X, Li X, Hoyos LR, Abbott DH, Chazenbalk GD. Adipose Insulin Resistance in Normal-Weight Polycystic Ovary Syndrome Women. J Clin Endocrinol Metab. 2019 Jan 11. doi: 10.1210/jc.2018-02086. PMID: 30649347
Hoyos LR, Vilchez G, Allsworth JE, Malik M, Rodriguez-Kovacs J, Adekola H, Awonuga AO. Outcomes in subsequent pregnancies after wedge resection for interstitial ectopic pregnancy: a retrospective cohort study J Matern Fetal Neonatal Med. 2018 Feb 15:1-7. doi: 10.1080/14767058.2018.1437411. PMID: 29400114
Hoyos LR, Malik MF, Najjar M, Rodriguez-Kovacs J, Abdallah M, Vilchez G, Awonuga AO. Morbid Obesity and Outcome of Ectopic Pregnancy Following Capped Single-Dose Regimen Methotrexate. Arch Gynecol Obstet. 2017 Feb;295(2):375-381. doi: 10.1007/s00404-016-4229-0. PMID: 27844211
Hoyos LR, Khan S, Dai J, Singh M, Diamond MP, Puscheck EE, Awonuga AO. Low dose urinary hCG is effective for oocyte maturation in IVF/ICSI cycles independent of body mass index. Int J Fertil Steril 2017 Apr-Jun;11(1):7-14. PMID: 28367299
Vilchez G, Hoyos LR, Leon-Peters J, Lagos M, Argoti P. Differences in clinical presentation and pregnancy outcomes in antepartum preeclampsia and new-onset postpartum preeclampsia: Are these the same disorder? Obstet Gynecol Sci. 2016 Nov;59(6):434-443. PMID: 27896245
Hoyos LR, Leon-Peters J, Berman JM, Hertz M. Pregnancy following hysteroscopic sterilization at an urban abortion clinic- a case series: Are we looking in the wrong places?. Contraception. 2016 Jul;94(1):78-80. doi: 10.1016/j.contraception.2016.02.028. PMID: 27000998 17. Vilchez GA, Hoyos LR, Maldonado MC, Lagos M, Bahado-Singh R. Risk of neonatal mortality according to gestational age after elective repeat cesarean delivery. Arch Gynecol Obstet. 2016 Jul;294(1):77-81. doi: 10.1007/s00404-015-3955-z. PMID: 26590575
Vilchez GA, Dai J, Hoyos LR, Gill N, Bahado-Singh R, Sokol RJ. Labor and neonatal outcomes after term induction of labor in gestational diabetes. J Perinatol. 2015 Nov;35(11):924-9. doi: 10.1038/jp.2015.103. PMID: 26313053
Vilchez GA, Londra LC, Hoyos LR, Sokol RJ, Bahado-Singh R. Intrapartum mean platelet volume is not a useful predictor of late-onset postpartum preeclampsia. Int J Gynaecol Obstet. 2015 Oct;131(1):59-62. doi: 10.1016/j.ijgo.2015.04.037. PMID: 26122464
Vilchez GA, Dai J, Hoyos LR, Chelliah A, Bahado-Singh R, Sokol RJ. Optimal timing for term twin delivery of twin pregnancies: a population-based study. Am J Perinatol. 2015 Apr;32(5):487-96. doi: 10.1055/s-0034-1396693. PMID: 25545449
Cardoso Medina B, Hernandez-Giraldo C, Riaño G, Hoyos LR, Otalora C. Barbed suture for vaginal cuff closure in laparoscopic hysterectomy. JSLS. 2014 Jan-Mar;18(1):83-8. doi: 10.4293/108680813X13693422518795. PMID: 24680149
Portilla D, Hernandez-Giraldo C, Moreno B, Quijano F, Hoyos LR, Angarita AM, Madero S. A local hemostatic agent for the management of postpartum hemorrhage due to placenta previa and placenta accreta: a cross-sectional study. Arch Gynecol Obstet. 2013 Sep;288(3):543-9. doi: 10.1007/s00404-013-2812-1. PMID: 23532388
Q&A with Luis R. Hoyos, M.D.
Why did you become a doctor/reproductive endocrinologist?
I always liked science and among the different ways I could devote a career to science, I found in medicine a field of knowledge which could be applied to help people on an every day basis. The calling to become a Reproductive Endocrinology & Infertility specialist did not come until later in medical school, when, during an assisted reproductive technology lecture, I became awestruck by the beautiful and marvelous interaction between ultimate science and patient care at the service of family building. I knew my calling at that time, and I feel very proud of my specialty and what we do for our patients.
What about IVF FLORIDA makes you the proudest
Every single member of our team and the way we care for our patients. Patient care is a team sport, and we have the best in the game.
Describe a time you were inspired by a patient.
It would be very difficult to refer back to a single patient when all of them inspire me every day. I am most inspired by their resilience and drive. They wake up every day committed to the process, and it is my duty to give them my unwavering attention and support as they go through. They keep me going, and wanting to help them is my “ikigai” (i.e., sense of purpose in life).
What is your approach to helping patients who are struggling?
Supporting them is my full-time job. Unfortunately, struggles may happen, and I make sure to make myself available to assist, guide, lift up or become their confidant in any way that I can. This is a process that is intrinsically human, very rooted in the fabric of our own nature. Therefore, I make sure to remain human and provide that human touch we all need during the difficult times of our lives.
What do you enjoy doing in your spare time?
When I’m not in the office, most of my time is spent relaxing with family and friends. When time allows, I love to travel. I find a lot of joy in visiting new places, experiencing the local food scene and taking history tours to learn as much as I can about the part of the world I am in.